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Gregory N Barnes

Gregory N Barnes, MD

Pediatric Neurology

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Highlights

Age Groups Seen

  • Pediatrics
  • Teenagers

Languages

  • English

Gender

Male

About Gregory N Barnes

Academic Title

Professor of Pediatrics

Recognition

Publications:

Research Articles:
O. Dekhil, M.Ismail, A.Shalaby, A.Switala, A.Elmaghraby, R. Keynton, G. Gimel'farb, G.N. Barnes, A.El-baz, (2017) A Novel CAD System for Autism Diagnosis Using Structural and Functional MRI, 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017), Melbourne, VIC, 2017, pp. 995-998. doi: 10.1109/ISBI.2017.7950683

El-Gamal FEA, Elmogy MM, Ghazal M, Atwan A, Casanova MF, Barnes GN, Keynton R, El-Baz AS, Khalil A. (2017)A Novel Early Diagnosis System for Mild Cognitive Impairment Based on Local Region Analysis: A Pilot Study. Frontiers in human neuroscience. 2017; 11:643.

Ismail M, Soliman A, Ghazal M, Switala AE, Gimel'farb G, Barnes GN, Khalil A, El-Baz A. (2017) A fast stochastic framework for automatic MR brain images segmentation. PloS one. 2017; 12(11):e0187391

E. Hosseine-Asl, M. Ghazal, A. Mahmoud, A. Aslantas, A. Shalaby, M. Casanova, G. N. Barnes, R. Keynton, and A. El-Baz, (2018) Alzheimer’s Disease Diagnostics by a 3D Deeply Supervised Adaptable Convolutional Network, Frontiers in Bioscience, Landmark, 23, 584-596, [January 1, 2018]

Fatma El-Zahraa A. El-Gamal, Mohammed M. Elmogy, Mohammed Ghazal, Ahmed Atwan, Manual F. Casanova, Gregory N. Barnes, Ayman S. El-Baz, Hassan Hajjdi (2018) Medical Imaging Diagnosis of Early Alzheimer’s disease. Frontiers in Bioscience, Landmark, 23, 671-725, [January 1, 2018]

Tan, W.H., Bird, L.M., Sadhwani, A., Barbieri-Welge, R.L., Skinner, S.A., Horowitz, L.T., Bacino, C.A., Noll, L.M., Fu, C, Wink, L.K., Erickson, C.A., Barnes, G.N., Slavtinek, A., Jeremy, R, Rotenberg, A, Kothare, S.V., Olson, H.E., Poduri, A, Nespeca, M.P., Chu, H.C., Willen, J.M., Haas, K.F., Weeber, E.J., and Rufo, P.A. (2018) A Randomized Controlled Trial of Levodopa in Patients with Angelman’s Syndrome, Am J. Med Genet., Part A. 2017

Kshama Ohja, Evelyne Gozal, Margaret Fahnestock, Lu Cai, Jun Cai, Jonathan H. Freedman, Andy Switala, Ayman El-Baz, and Gregory Barnes. (2018) Neuroimmunologic and Neurotrophic Interactions in Autism Spectrum Disorders: Relationship to Neuroinflammation. NeuroMolecular Medicine, in press

Book Chapter:
G.N. Barnes, (2015) “Epilepsy” book chapter in Neinstein’s Adolescent and Young Adult Medicine. LWW publisher, New York City, NY

Clinical Interests/Research

Clinical Interests:

Epilepsy, Autism, Pediatrics

Research Interests:

Autism and epilepsy are common childhood neurological disorders with a great heterogeneity of clinical phenotypes as well as risk factors. There is a high co-morbidity of autism and epilepsy but the molecular underpinnings of this overlap are unclear. The neuropathology of autism and epilepsy has distinctly similar histology implicating the processes of neurogenesis, neural migration, programmed cell death, and neurite outgrowth. Genetic advances have identified multiple molecules that participate in neural development, brain network connectivity, and synaptic function which could be involved in the pathogenesis of autism including the guidance system Semaphorin 3F-Neuropilin 2 signaling. Dr Barnes’ clinical and basic science research program investigates the genomic determinants of behavior and cognition in human and animal models of autism and epilepsy. The long term goals of this research is to conduct studies in models of autism and epilepsy to aid in the identification of therapeutic drug targets to ameliorate the burden of neurologic disease in these children. Special emphasis is placed on the understanding of the contribution of GABAergic signaling, epileptiform discharges and sleep to epileptogenesis and behavior in the broad ASD populations

Video

Locations

  1. Norton Children's Autism Center
    • phone: 502-588-0736
    • fax: 502-588-0721

Expertise

Education

  • Residency: Boston Children's Hospital, Neurology, 1997
  • Residency: St. Louis Children's Hospital, Pediatrics, 1994
  • Medical Education: University of Kentucky College of Medicine, Doctor of Medicine, 1992

Board Certifications

  • Epilepsy: American Board of Psychiatry and Neurology, 2013
  • Pediatrics: American Board of Pediatrics, 1999
  • Neurology with Special Qualification in Child Neurology: American Board of Psychiatry and Neurology, 1998

Insurance

Please contact the practice directly to confirm your health plan is in network.
Search plans
  • Aetna
  • Aetna Better Health
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  • Anthem Pathway Transition
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  • CareSource Marketplace Kentucky and Indiana
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  • First Health Group Corp. (First Health)
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  • United Healthcare Community Plan Indiana and Kentucky
  • United Healthcare Medicare Advantage
  • UofL Health – Frazier Rehabilitation Institute
  • Veterans Affairs (VA)
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  • WellCare Medicare
  • WellCare of Kentucky Medicaid (Kentucky MCO)
  • Wellpath
  • Workers’ Compensation